The neural implementation of operant conditioning with few trials is unclear. We propose a Hippocampus-Inspired Cognitive Architecture (HICA) as a neural mechanism for operant conditioning. HICA explains a learning mechanism in which agents can learn a new behavior policy in a few trials, as mammals do in operant conditioning experiments. HICA is composed of two different types of modules. One is a universal learning module type that represents a cortical column in the neocortex gray matter. The working principle is modeled as Modulated Heterarchical Prediction Memory (mHPM). In mHPM, each module learns to predict a succeeding input vector given the sequence of the input vectors from lower layers and the context vectors from higher layers. The prediction is fed into the lower layers as a context signal (top-down feedback signaling), and into the higher layers as an input signal (bottom-up feedforward signaling). Rewards modulate the learning rate in those modules to memorize meaningful sequences effectively. In mHPM, each module updates in a local and distributed way compared to conventional end-to-end learning with backpropagation of the single objective loss. This local structure enables the heterarchical network of modules. The second type is an innate, special-purpose module representing various organs of the brain's subcortical system. Modules modeling organs such as the amygdala, hippocampus, and reward center are pre-programmed to enable instinctive behaviors. The hippocampus plays the role of the simulator. It is an autoregressive prediction model of the top-most level signal with a loop structure of memory, while cortical columns are lower layers that provide detailed information to the simulation. The simulation becomes the basis for learning with few trials and the deliberate planning required for operant conditioning.

Despite recent advances of AI research in many application-specific domains, we do not know how to build a human-level artificial intelligence (HLAI). We conjecture that learning from others' experience with the language is the essential characteristic that distinguishes human intelligence from the rest. Humans can update the action-value function with the verbal description as if they experience states, actions, and corresponding rewards sequences firsthand. In this paper, we present a classification of intelligence according to how individual agents learn and propose a definition and a test for HLAI. The main idea is that language acquisition without explicit rewards can be a sufficient test for HLAI.

Unsupervised learning-based anomaly detection in latent space has gained importance since discriminating anomalies from normal data becomes difficult in high-dimensional space. Both density estimation and distance-based methods to detect anomalies in latent space have been explored in the past. These methods prove that retaining valuable properties of input data in latent space helps in the better reconstruction of test data. Moreover, real-world sensor data is skewed and non-Gaussian in nature, making mean-based estimators unreliable for skewed data. Again, anomaly detection methods based on reconstruction error rely on Euclidean distance, which does not consider useful correlation information in the feature space and also fails to accurately reconstruct the data when it deviates from the training distribution. In this work, we address the limitations of reconstruction error-based autoencoders and propose a kernelized autoencoder that leverages a robust form of Mahalanobis distance (MD) to measure latent dimension correlation to effectively detect both near and far anomalies. This hybrid loss is aided by the principle of maximizing the mutual information gain between the latent dimension and the high-dimensional prior data space by maximizing the entropy of the latent space while preserving useful correlation information of the original data in the low-dimensional latent space. The multi-objective function has two goals -- it measures correlation information in the latent feature space in the form of robust MD distance and simultaneously tries to preserve useful correlation information from the original data space in the latent space by maximizing mutual information between the prior and latent space.

The Internet of Things (IoT) is a system that connects physical computing devices, sensors, software, and other technologies. Data can be collected, transferred, and exchanged with other devices over the network without requiring human interactions. One challenge the development of IoT faces is the existence of anomaly data in the network. Therefore, research on anomaly detection in the IoT environment has become popular and necessary in recent years. This survey provides an overview to understand the current progress of the different anomaly detection algorithms and how they can be applied in the context of the Internet of Things. In this survey, we categorize the widely used anomaly detection machine learning and deep learning techniques in IoT into three types: clustering-based, classification-based, and deep learning based. For each category, we introduce some state-of-the-art anomaly detection methods and evaluate the advantages and limitations of each technique.

Pneumonia, a respiratory infection brought on by bacteria or viruses, affects a large number of people, especially in developing and impoverished countries where high levels of pollution, unclean living conditions, and overcrowding are frequently observed, along with insufficient medical infrastructure. Pleural effusion, a condition in which fluids fill the lung and complicate breathing, is brought on by pneumonia. Early detection of pneumonia is essential for ensuring curative care and boosting survival rates. The approach most usually used to diagnose pneumonia is chest X-ray imaging. The purpose of this work is to develop a method for the automatic diagnosis of bacterial and viral pneumonia in digital x-ray pictures. This article first presents the authors' technique, and then gives a comprehensive report on recent developments in the field of reliable diagnosis of pneumonia. In this study, here tuned a state-of-the-art deep convolutional neural network to classify plant diseases based on images and tested its performance. Deep learning architecture is compared empirically. VGG19, ResNet with 152v2, Resnext101, Seresnet152, Mobilenettv2, and DenseNet with 201 layers are among the architectures tested. Experiment data consists of two groups, sick and healthy X-ray pictures. To take appropriate action against plant diseases as soon as possible, rapid disease identification models are preferred. DenseNet201 has shown no overfitting or performance degradation in our experiments, and its accuracy tends to increase as the number of epochs increases. Further, DenseNet201 achieves state-of-the-art performance with a significantly a smaller number of parameters and within a reasonable computing time. This architecture outperforms the competition in terms of testing accuracy, scoring 95%. Each architecture was trained using Keras, using Theano as the backend.

Diabetic Retinopathy (DR) is a leading cause of vision loss in the world, and early DR detection is necessary to prevent vision loss and support an appropriate treatment. In this work, we leverage interactive machine learning and introduce a joint learning framework, termed DRG-Net, to effectively learn both disease grading and multi-lesion segmentation. Our DRG-Net consists of two modules: (i) DRG-AI-System to classify DR Grading, localize lesion areas, and provide visual explanations; (ii) DRG-Expert-Interaction to receive feedback from user-expert and improve the DRG-AI-System. To deal with sparse data, we utilize transfer learning mechanisms to extract invariant feature representations by using Wasserstein distance and adversarial learning-based entropy minimization. Besides, we propose a novel attention strategy at both low- and high-level features to automatically select the most significant lesion information and provide explainable properties. In terms of human interaction, we further develop DRG-Net as a tool that enables expert users to correct the system's predictions, which may then be used to update the system as a whole. Moreover, thanks to the attention mechanism and loss functions constraint between lesion features and classification features, our approach can be robust given a certain level of noise in the feedback of users. We have benchmarked DRG-Net on the two largest DR datasets, i.e., IDRID and FGADR, and compared it to various state-of-the-art deep learning networks. In addition to outperforming other SOTA approaches, DRG-Net is effectively updated using user feedback, even in a weakly-supervised manner.

The ability to distinguish between different movie scenes is critical for understanding the storyline of a movie. However, accurately detecting movie scenes is often challenging as it requires the ability to reason over very long movie segments. This is in contrast to most existing video recognition models, which are typically designed for short-range video analysis. This work proposes a State-Space Transformer model that can efficiently capture dependencies in long movie videos for accurate movie scene detection. Our model, dubbed TranS4mer, is built using a novel S4A building block, which combines the strengths of structured state-space sequence (S4) and self-attention (A) layers. Given a sequence of frames divided into movie shots (uninterrupted periods where the camera position does not change), the S4A block first applies self-attention to capture short-range intra-shot dependencies. Afterward, the state-space operation in the S4A block is used to aggregate long-range inter-shot cues. The final TranS4mer model, which can be trained end-to-end, is obtained by stacking the S4A blocks one after the other multiple times. Our proposed TranS4mer outperforms all prior methods in three movie scene detection datasets, including MovieNet, BBC, and OVSD, while also being $2\times$ faster and requiring $3\times$ less GPU memory than standard Transformer models. We will release our code and models.

Several self-supervised representation learning methods have been proposed for reinforcement learning (RL) with rich observations. For real-world applications of RL, recovering underlying latent states is crucial, particularly when sensory inputs contain irrelevant and exogenous information. In this work, we study how information bottlenecks can be used to construct latent states efficiently in the presence of task-irrelevant information. We propose architectures that utilize variational and discrete information bottlenecks, coined as RepDIB, to learn structured factorized representations. Exploiting the expressiveness bought by factorized representations, we introduce a simple, yet effective, bottleneck that can be integrated with any existing self-supervised objective for RL. We demonstrate this across several online and offline RL benchmarks, along with a real robot arm task, where we find that compressed representations with RepDIB can lead to strong performance improvements, as the learned bottlenecks help predict only the relevant state while ignoring irrelevant information.

An expansion of aberrant brain cells is referred to as a brain tumor. The brain's architecture is extremely intricate, with several regions controlling various nervous system processes. Any portion of the brain or skull can develop a brain tumor, including the brain's protective coating, the base of the skull, the brainstem, the sinuses, the nasal cavity, and many other places. Over the past ten years, numerous developments in the field of computer-aided brain tumor diagnosis have been made. Recently, instance segmentation has attracted a lot of interest in numerous computer vision applications. It seeks to assign various IDs to various scene objects, even if they are members of the same class. Typically, a two-stage pipeline is used to perform instance segmentation. This study shows brain cancer segmentation using YOLOv5. Yolo takes dataset as picture format and corresponding text file. You Only Look Once (YOLO) is a viral and widely used algorithm. YOLO is famous for its object recognition properties. You Only Look Once (YOLO) is a popular algorithm that has gone viral. YOLO is well known for its ability to identify objects. YOLO V2, V3, V4, and V5 are some of the YOLO latest versions that experts have published in recent years. Early brain tumor detection is one of the most important jobs that neurologists and radiologists have. However, it can be difficult and error-prone to manually identify and segment brain tumors from Magnetic Resonance Imaging (MRI) data. For making an early diagnosis of the condition, an automated brain tumor detection system is necessary. The model of the research paper has three classes. They are respectively Meningioma, Pituitary, Glioma. The results show that, our model achieves competitive accuracy, in terms of runtime usage of M2 10 core GPU.

Artificial intelligence(AI) systems based on deep neural networks (DNNs) and machine learning (ML) algorithms are increasingly used to solve critical problems in bioinformatics, biomedical informatics, and precision medicine. However, complex DNN or ML models that are unavoidably opaque and perceived as black-box methods, may not be able to explain why and how they make certain decisions. Such black-box models are difficult to comprehend not only for targeted users and decision-makers but also for AI developers. Besides, in sensitive areas like healthcare, explainability and accountability are not only desirable properties of AI but also legal requirements -- especially when AI may have significant impacts on human lives. Explainable artificial intelligence (XAI) is an emerging field that aims to mitigate the opaqueness of black-box models and make it possible to interpret how AI systems make their decisions with transparency. An interpretable ML model can explain how it makes predictions and which factors affect the model's outcomes. The majority of state-of-the-art interpretable ML methods have been developed in a domain-agnostic way and originate from computer vision, automated reasoning, or even statistics. Many of these methods cannot be directly applied to bioinformatics problems, without prior customization, extension, and domain adoption. In this paper, we discuss the importance of explainability with a focus on bioinformatics. We analyse and comprehensively overview of model-specific and model-agnostic interpretable ML methods and tools. Via several case studies covering bioimaging, cancer genomics, and biomedical text mining, we show how bioinformatics research could benefit from XAI methods and how they could help improve decision fairness.